Papers | Human Nature Lab | Human Nature Lab at Yale

Characterization of gut microbiomes in rural Honduras reveals uncharacterized species and associations with human genetic variation

6 | Biomarker , Evolutionary Biology , Genetics , Honduras , LMIC , Microbiome

Citation:

Beghini F, Brito IL, Gerstein M, Christakis NA. Characterization of gut microbiomes in rural Honduras reveals uncharacterized species and associations with human genetic variation. Cell Rep. 2026 Jan 27;45(1):116724. doi: 10.1016/j.celrep.2025.116724. Epub 2025 Dec 18. PMID: 41420859.

Social Networks and International Migration in Honduran Villages

8 | Geographic Effects , Global Health , Honduras , LMIC , PNAS , Social Contagion , Social Network , Sociocentric Network

Citation:

Thomas LJ, Christakis NA, Garip F. Social networks and international migration in Honduran villages. Proc Natl Acad Sci U S A. 2026 Jan 6;123(1):e2505818122. doi: 10.1073/pnas.2505818122. Epub 2026 Jan 2. PMID: 41481447; PMCID: PMC12773785.

Network-cycle motif participation is associated with individual and collective wealth in Honduran villages

8 | Economics , Honduras , Inequality , LMIC , Methodology , Social Network , Sociocentric Network , Trellis Software

Citation:

Shridhar, S.V., Lee, S.T., Charette, Y. et al. Network-cycle motif participation is associated with individual and collective wealth in Honduran villages. Sci Rep 15, 27680 (2025).

Realism Drives Interpersonal Reciprocity but Yields to AI-Assisted Egocentrism in a Coordination Experiment

6 | Artificial Intelligence (AI) , Breadboard Software , Cooperation , Experiment , Methodology , Public Goods

Citation:

Hirokazu Shirado, Kye Shimizu, Nicholas A Christakis, and Shunichi Kasahara. 2025. Realism Drives Interpersonal Reciprocity but Yields to AI-Assisted Egocentrism in a Coordination Experiment. In CHI Conference on Human Factors in Computing Systems (CHI ’25), April 26–May 01, 2025, Yokohama, Japan. ACM, New York, NY

Cognitive representations of social networks in isolated villages

11 | Friendship , Honduras , Indigenous Social Network , Genetics , LMIC , Methodology , Multiplex Network , NAC Favorite , Social Network , Sociocentric Network , Trellis Software

Citation:

Feltham, E., Forastiere, L. & Christakis, N.A. Cognitive representations of social networks in isolated villages. Nat Hum Behav (2025). https://doi.org/10.1038/s41562-025-02221-6

Antidepressant use in spatial social networks

5 | Geographic Effects , Happiness , Health Services Research , Online Network , Social Network

Citation:

Lengyel B, Tóth G, Christakis NA, Bíró A. Antidepressant use in spatial social networks. Sci Adv. 2024 Dec 6;10(49):eadr0302. doi: 10.1126/sciadv.adr0302. Epub 2024 Dec 6. PMID: 39642229; PMCID: PMC11623294.

Bringing leaders of network subgroups closer together does not facilitate consensus

5 | Breadboard Software , Experiment , Position Intervention , Social Network , Public Goods

Citation:

Matthew I. Jones, Nicholas A. Christakis. Bringing leaders of network subgroups closer together does not facilitate consensus. Scientific Reports, Dec 4;14(1):30183.

Gut Microbiome Strain-sharing within Isolated Village Social Networks (Nature, 2024)

14 | Friendship , Genetics , Global Health , Homophily , Honduras , Indigenous Social Network , Infectious Disease , LMIC , Microbiome , NAC Favorite , Nature , Social Network , Sociocentric Network , Trellis Software

Citation:

Beghini F, Pullman J, Alexander M, Shridhar SV, Prinster D, Singh A, Matute Juárez R, Airoldi EM, Brito IL, Christakis NA. Gut microbiome strain-sharing within isolated village social networks. Nature. 2025 Jan;637(8044):167-175. doi: 10.1038/s41586-024-08222-1. Epub 2024 Nov 20. PMID: 39567691; PMCID: PMC11666459.

Systematic review of methods to discern antagonistic ties in social networks in community settings

2 | Antagonistic Networks , Methodology

Citation:

Ana Lucia Rodriguez de la Rosa, Karina Raygoza Cortez, Alice Lu, Bianka Valentin, Amir Ghasemian, Nicholas Christakis. Systematic review of methods to discern antagonistic ties in social networks in community settings. Social Sciences & Humanities Open, Volume 10, 2024, 101039, ISSN 2590-2911.

Environmental, socioeconomic, and health factors associated with gut microbiome species and strains in isolated Honduras villages

10 | Biomarker , Cardiovascular Disease , Geographic Effects , Global Health , Honduras , Indigenous Social Network , LMIC , Mental Health , Microbiome , Trellis Software

Citation:

Shridhar SV, Beghini F, Alexander M, Singh A, Juárez RM, Brito IL, Christakis NA. Environmental, socioeconomic, and health factors associated with gut microbiome species and strains in isolated Honduras villages. Cell Reports. 2024 Jul 3;43(7):114442. doi: 10.1016/j.celrep.2024.114442. Epub ahead of print. PMID: 38968070.